Posts by: Alice Melao

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Increasing levels of the mitofusin-1 (MFN1) protein in nerve cells of the spinal cord can reverse the features of Charcot-Marie-Tooth type 2A (CMT2A), a study in mice shows. The ... Read more

February 5, 2019February 5, 2019

New Cell Model Sheds Light on MTMR13 Enzyme’s Role in Myelin Production in CMT4B2

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A new experimental model of Charcot-Marie-Tooth disease (CMT) type 4B2 sheds light on the role of the MTMR13 enzyme in the abnormal production of myelin known to be involved in ... Read more

January 22, 2019January 22, 2019

Modulation of Specific Molecule May Help Treat Subtypes of CMT, Study Shows

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Modulation of Nrg1TIII signals improves production of the nerve cells’ myelin protective layer in mice with Charcot-Marie-Tooth type 1B, a study shows. Reactivation of these signals or inhibition of ... Read more

January 8, 2019January 8, 2019

CMT2S Patients May Benefit from Respiratory Surveillance, Case Report Shows

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Patients with Charcot-Marie-Tooth disease (CMT) type 2S may benefit from lifelong respiratory surveillance, a case report suggests. The study, “Charcot Marie Tooth disease type 2S with late onset diaphragmatic ... Read more

October 19, 2018October 19, 2018

International CMT&Me Observational Study to Explore the Impact of CMT Using an App

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A newly launched international observational study is going to explore the overall impact of Charcot-Marie-Tooth disease (CMT) using a tailored app called CMT&Me. Designed by Vitaccess in collaboration with ... Read more

September 10, 2018September 10, 2018

RNA Molecule Can Regulate Common Pathway of CMT and ALS, Fruit Fly Study Suggests

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A genetic study in fruit flies has found a new link between Charcot-Marie-Tooth (CMT) disease and amyotrophic lateral sclerosis (ALS). Conducted by researchers from the Kyoto Institute of Technology ... Read more

July 30, 2018July 30, 2018

PNF Exercises Can Help CMT1A Patients Prevent Foot Drop, Study Suggests

News

Proprioceptive neuromuscular facilitation (PNF) muscle-stretching exercises can help prevent foot drop in patients with Charcot-Marie-Tooth (CMT) disease type 1A. The finding is reported in the study “Ipsilateral proprioceptive neuromuscular ... Read more

July 29, 2018August 29, 2018

PNKP Mutation Causes CMT2 in Large Costa Rican Family, Genetic Study Reveals

News

A reanalysis of the genetic profile of a large Costa Rican family revealed that a PNKP gene mutation was to blame for Charcot-Marie-Tooth disease type 2 (CMT2) and not ... Read more

June 18, 2018June 18, 2018

Flex Pharma Halts Phase 2 FLX-787 Trial in CMT Patients Due to Tolerability Concerns

News

Flex Pharma is terminating a Phase 2 clinical trial that was assessing FLX-787 as a potential treatment for muscle cramps in Charcot-Marie-Tooth disease (CMT) patients due to concerns about ... Read more

May 25, 2018May 25, 2018

Muscle Weakness Due to Overuse Evident in Dominant Hands of CMT Patients, Study Reports

News

Muscle weakness due to excessive or repetitive muscle use, a symptom known as “overwork weakness,” is evident in the hands of patients with Charcot‐Marie‐Tooth (CMT) disease, a study reported, ... Read more

Posts by: Alice Melao

Alice Melao

Increased Levels of MFN1 Protein Can Reverse Features of CMT2A in Mice, Study Shows

New Cell Model Sheds Light on MTMR13 Enzyme’s Role in Myelin Production in CMT4B2

Modulation of Specific Molecule May Help Treat Subtypes of CMT, Study Shows

CMT2S Patients May Benefit from Respiratory Surveillance, Case Report Shows

International CMT&Me Observational Study to Explore the Impact of CMT Using an App

RNA Molecule Can Regulate Common Pathway of CMT and ALS, Fruit Fly Study Suggests

PNF Exercises Can Help CMT1A Patients Prevent Foot Drop, Study Suggests

PNKP Mutation Causes CMT2 in Large Costa Rican Family, Genetic Study Reveals

Flex Pharma Halts Phase 2 FLX-787 Trial in CMT Patients Due to Tolerability Concerns

Muscle Weakness Due to Overuse Evident in Dominant Hands of CMT Patients, Study Reports

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