Posts by: Alice Melao

News

A newly launched international observational study is going to explore the overall impact of Charcot-Marie-Tooth disease (CMT) using a tailored app called CMT&Me. Designed by Vitaccess in collaboration with ... Read more

September 10, 2018September 10, 2018

RNA Molecule Can Regulate Common Pathway of CMT and ALS, Fruit Fly Study Suggests

News

A genetic study in fruit flies has found a new link between Charcot-Marie-Tooth (CMT) disease and amyotrophic lateral sclerosis (ALS). Conducted by researchers from the Kyoto Institute of Technology ... Read more

July 30, 2018July 30, 2018

PNF Exercises Can Help CMT1A Patients Prevent Foot Drop, Study Suggests

News

Proprioceptive neuromuscular facilitation (PNF) muscle-stretching exercises can help prevent foot drop in patients with Charcot-Marie-Tooth (CMT) disease type 1A. The finding is reported in the study “Ipsilateral proprioceptive neuromuscular ... Read more

July 29, 2018August 29, 2018

PNKP Mutation Causes CMT2 in Large Costa Rican Family, Genetic Study Reveals

News

A reanalysis of the genetic profile of a large Costa Rican family revealed that a PNKP gene mutation was to blame for Charcot-Marie-Tooth disease type 2 (CMT2) and not ... Read more

June 18, 2018June 18, 2018

Flex Pharma Halts Phase 2 FLX-787 Trial in CMT Patients Due to Tolerability Concerns

News

Flex Pharma is terminating a Phase 2 clinical trial that was assessing FLX-787 as a potential treatment for muscle cramps in Charcot-Marie-Tooth disease (CMT) patients due to concerns about ... Read more

May 25, 2018May 25, 2018

Muscle Weakness Due to Overuse Evident in Dominant Hands of CMT Patients, Study Reports

News

Muscle weakness due to excessive or repetitive muscle use, a symptom known as “overwork weakness,” is evident in the hands of patients with Charcot‐Marie‐Tooth (CMT) disease, a study reported, ... Read more

May 21, 2018May 21, 2018

Micro RNA Variant Found that May Be Linked to CMT1A Outcomes

News

A specific mutation in a small RNA molecule called miR-149 was found to be linked to both age of onset and severity in patients with Charcot-Marie-Tooth disease type 1A (CMT1A), ... Read more

May 16, 2018May 16, 2018

Tumor Suppressor Enzyme May Be Therapeutic Target for CMT4J, Study Suggests

News

Inhibition of a tumor suppressor enzyme called MST1 could reverse the effects of the genetic mutations that cause Charcot-Marie-Tooth disease type 4J (CMT4J), researchers show in a fruit fly ... Read more

May 9, 2018May 9, 2018

Researchers Develop New Approach to ID Genetic Contributors for CMT

News

Researchers at University of Michigan developed a new method that can help identify potential targets relevant for normal peripheral nerve activity and Charcot-Marie-Tooth (CMT) disease therapy development. Based on genetic ... Read more

April 16, 2018April 16, 2018

Clinical Trial to Test New Tool for Assessing CMT’s Severity in Children

News

The Inherited Neuropathies Consortium will conduct a clinical trial of a tool that researchers developed to assess the severity of children’s Charcot-Marie-Tooth Disease. Scientists say the assessment tool used in adults ... Read more

Posts by: Alice Melao

Alice Melao

International CMT&Me Observational Study to Explore the Impact of CMT Using an App

RNA Molecule Can Regulate Common Pathway of CMT and ALS, Fruit Fly Study Suggests

PNF Exercises Can Help CMT1A Patients Prevent Foot Drop, Study Suggests

PNKP Mutation Causes CMT2 in Large Costa Rican Family, Genetic Study Reveals

Flex Pharma Halts Phase 2 FLX-787 Trial in CMT Patients Due to Tolerability Concerns

Muscle Weakness Due to Overuse Evident in Dominant Hands of CMT Patients, Study Reports

Micro RNA Variant Found that May Be Linked to CMT1A Outcomes

Tumor Suppressor Enzyme May Be Therapeutic Target for CMT4J, Study Suggests

Researchers Develop New Approach to ID Genetic Contributors for CMT

Clinical Trial to Test New Tool for Assessing CMT’s Severity in Children

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