Author Archives: Alice Melao

Large-scale Study Reveals Gender-specific Features of CMTX1

X-linked Charcot-Marie-Tooth disease (CMTX1) affects men and women differently, finds a large-scale study promoted by the Inherited Neuropathies Consortium. The study. “Cross-sectional analysis of a large cohort with X-linked Charcot-Marie-Tooth disease (CMTX1),” appeared in the journal Neurology. CMT is an inherited genetic disease that affects the…

Melatonin Lowers Inflammation, Oxidation in Charcot-Marie-Tooth Disease, Study Reports

Melatonin can significantly decrease inflammation and oxidative stress markers that may be related to the progression of Charcot-Marie-Tooth disease, a Spanish study reports. The study, which appeared in the journal Molecules, was titled “Melatonin Treatment Reduces Oxidative Damage and Normalizes Plasma Pro-Inflammatory Cytokines in Patients Suffering from Charcot-Marie-Tooth Neuropathy:…

Researchers Identify New Mutation in Gene Linked to CMT Type 4H

Researchers identified a novel genetic mutation affecting the FGD4 gene in a patient with Charcot-Marie-Tooth disease type 4H (CMT4H). With an early onset, CMT4 is a slow progressive neurological disease caused by genetic variations in genes involved in nerve cells function or structure. In the CMT4H subtype, several…