News

To promote physical activity in people with Charcot-Marie-Tooth (CMT) disease, the charity CMT UK shared seven exercise videos that patients can carry out in the comfort of their home. The exercises are presented by Rebekah Knight, a physiotherapist diagnosed with CMT1A, the most common form of CMT…

A majority of rare disease patients using telehealth during the COVID-19 pandemic thought the experience positive, and many would like the option of continuing its use in future appointments, a series of surveys found. The surveys were conducted by the National Organization for Rare Disorders (NORD) and involved more than 800…

Patients with Charcot Marie Tooth Type 1A (CMT1A) disease appear to experience a structural reorganization in their brains, particularly in a region associated with movement and balance called the cerebellum, a recent study found. These alterations, researchers suggest, may be a…

A new formulation of an antioxidant called curcumin may be effective in alleviating the symptoms of Charcot-Marie-Tooth type 1A (CMT1A) disease, a rat study suggests. The formulation was seen to lower oxidative stress and promote nerve cell myelination in a CMT1A rat model, ultimately leading to better sensory…

Using bioinformatics — computer-based analyses of biological data — scientists discovered 30 new genes that might be involved in Charcot-Marie-Tooth disease (CMT). Their findings also provide new insights into the biological processes and gene interactions at play in CMT, further expanding the current knowledge and understanding of the…

Same But Different, a nonprofit U.K. group that uses art for social change, is inviting people to choose their favorite photographs in a calendar contest to heighten awareness of rare diseases, including amyotrophic lateral sclerosis (ALS). The organization’s panel of judges has pared the number of contest submissions…

Blocking a protein called CMTM6 in myelin-producing cells increases the thickness of nerve fibers and the speed at which electrical signals travel along their length, a mouse study has found. Based on these findings, researchers argued that blocking the activity of this protein may be a valuable therapeutic approach…

This October, in observance of Charcot-Marie-Tooth disease (CMT) awareness month in Europe, the CMT&Me study is launching an international competition aimed at informing people about this group of inherited disorders, and raising funds for research, according to a press release. The competition only requires that patients in…

The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health (NIH), has awarded DTx Pharma a funding grant to advance development of promising new therapeutic candidates for Charcot-Marie-Tooth (CMT) type 1A (CMT1A) disease. The therapeutic candidates are specially designed RNA oligonucleotide…

Three new genetic mutations in the GJB1 gene have been found inn Chinese patients that can cause X-linked Charcot-Marie-Tooth (CMTX1) disease, expanding the diversity of mutations causing the condition, according to a study. While the three mutations were all in coding regions, some previously known mutations were…