Author Archives: Steve Bryson PhD

Neuropathic Pain Can Be Evident Across Various Types of CMT

Neuropathic pain, related to damage or impairment in nerve receptors that detect pain and heat, is most common in CMT1A patients but can be found in people with different types of Charcot–Marie Tooth (CMT) disease, a study found. Abnormal electrical signals along nerve fibers in response to heat generated…

CMT1 May Have Increased Boy’s Susceptibility to Rare Eye Palsy

A boy who experienced oculomotor nerve palsy, a rare condition affecting a nerve that controls eye movements, was later diagnosed with Charcot-Marie-Tooth disease type 1 (CMT1), a case study reports. Although the two conditions may have been coincidental, researchers noted the underlying nerve damage due to CMT may have…

Genetic Study Finds Novel CMT-linked Mutations

New genetic analysis tools identified previously unknown genetic mutations in people diagnosed with various types and subtypes of Charcot-Marie-Tooth (CMT) disease, a study reveals. The new techniques used to discern different genes and rare variants may enable researchers to improve detection rates of this neuropathic disorder. The study, “…

Study Reveals Genetic Makeup of CMT Patients in Central South China

Genetic analysis conducted by researchers in China has advanced the understanding of Charcot-Marie-Tooth (CMT) disease and related disorders, a study suggests. The analysis revealed a relatively higher proportion of those with subtype CMT2 and a lower occurrence of PMP22 gene duplication, a common genetic defect linked to the condition,…

Ultra Rare CMT Subtype 2Z Identified in 4 Chinese Families

Scientists in China examined the relationship between genetic mutations in the MORC2 gene and the various disease characteristics in people with the rare Charcot-Marie-Tooth disease subtype 2Z (CMT2Z).  Physicians should consider their study’s findings when working to diagnose unresolved cases showing…