HDAC6 Inhibitors Restore Neuromuscular Defects in Zebrafish
Treatment with inhibitors of the HDAC6 protein, including the new compound CKD-504, was able to restore proper connections between nerves and muscles and improve movement in zebrafish with low levels of GARS — the gene implicated in Charcot-Marie-Tooth disease type 2D, a study found. The results suggest that HDAC6 blockade may…