Steve Bryson, PhD,  science writer—

Two genetic mutations that cause subtypes of Charcot-Marie-Tooth (CMT) disease are not common in Iranian CMT type 4 patients, despite their high prevalence in other similar populations with consanguineous marriage, a study has found.  One new mutation was identified in…

Mutations that affect special enzymes crucial for protein production and closely associated with Charcot-Marie-Tooth (CMT) disease cause changes to their shape and flexibility. The degree of change to these proteins appears to determine disease severity, a recent study reports. The study, “…