Researchers found that small molecules which target the key protein altered in patients with Charcot-Marie-Tooth disease type 2A (CMT2A) may…
Articles by José Lopes, PhD
Damage in the nerves that control involuntary body functions — known as autonomic nerve damage — is highly prevalent and…
A specific portion of a protein contributes to the stability of myelin, the coating that protects nerve cells, according to…
Researchers have discovered that a molecular mechanism involving critical proteins for nervous system development may help explain targeted neuromuscular defects…
An abnormal protein interaction that led to nerve fiber degeneration in a mouse model of Charcot-Marie-Tooth (CMT) disease type…
Researchers described the case of a family with Charcot-Marie-Tooth (CMT) disease type 4J that has two mutations in the FIG4…
A woman with Charcot–Marie–Tooth disease was unable to regulate her body temperature, experiencing heat surges and an inability to sweat, according…
For the first time, protein biomarkers of Charcot-Marie-Tooth disease type 2 (CMT2) have been identified, which may help in the…
Researchers have revealed 3D images of a critical protein complex that provide an essential foundation to better understand the underlying…
Researchers discovered that the enzyme HDAC6 can serve as a potential therapeutic target in certain gene mutations related to Charcot-Marie…